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Bitroziga®(Abirateron)

Bitroziga®(Abirateron)

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قيّمها : 

250,500 mg film coated tablets

Abiraterone is an androgen biosynthesis inhibitor.




تنصح ل

Bitroziga® is a CYP17 inhibitor indicated in combination with prednisone for the treatment of patients with:


metastatic castration-resistant prostate cancer (CRPC). 
metastatic high-risk castration-sensitive prostate cancer (CSPC). 
It is not known if Bitroziga® is safe and effective in females or children.

وصف

Metastatic castration-resistant prostate cancer:
Bitroziga® 1000 mg (two 500 mg tablets or four 250 mg tablets) orally once daily with prednisone 5 mg orally twice daily. 

Metastatic castration-sensitive prostate cancer: 
Bitroziga® 1000 mg (two 500 mg tablets or four 250 mg tablets) orally once daily with prednisone 5 mg orally once daily. 

رأس المواصفات
مزايا

-High blood pressure (hypertension), low blood potassium levels (hypokalemia), fluid retention (edema), and irregular heartbeats

-Adrenal problems

-Increased risk of bone fracture

-Severe low blood sugar (hypoglycemia)

-Skeletal muscle effects

سلبيات

Since the drug interactions with Bitroziga® is not limited to the following medicines tell your healthcare provider or pharmacist if you are taking, have recently taken or might take any other medicines. This includes herbal medicines and other medicines you bought without a prescription. 

It is especially important to tell your doctor if you are taking, or have recently taken any of the following medicines. Some medicines may affect the way Bitroziga® works or Bitroziga® may affect how other medicines work. These medicines include some medicines in the following groups: 

- heart medicines (e.g. quinidine, procainamide, amiodarone and sotalol) 
- tranquilizers
- medicines for diabetes (e.g., pioglitazone)
- herbal medicines (e.g., St John’s wort) 
- Androgen deprivation treatment 
- methadone – used for pain relief and part of drug addiction detoxification
- moxifloxacin and rifampin– medicines used to treat infections 
- antipsychotics – used for serious mental illnesses (e.g., thioridazine)
- Dextromethorphan- cough suppressants

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